Regenerative medicine is a relatively new field that brings together experts in biology, chemistry, computer science, engineering, genetics, medicine, robotics, and other fields to find solutions to some of the most challenging medical problems faced by humankind.

When injured or invaded by disease, our bodies have the innate response to heal and defend. What if it was possible to harness the power of the body to heal and then accelerate it in a clinically relevant way? What if we could help the body to heal?

The promising field of Regenerative Medicine is working to restore structure and function of damaged tissues and organs. It is also creating solutions for organs that become permanently damaged. The goal of this approach is to find a way to cure previously untreatable injuries and diseases and avoid radical measures.

Combinations of these approaches can amplify our natural healing process in the places it is needed most, or take over the function of a permanently damaged organ.

How this can be done?

Many millions of adult stem cells are found in every human. Our body uses stem cells as one way of repairing itself. Studies have illustrated that if adult stem cells are harvested and then injected at the site of diseased or damaged tissue, reconstruction of the tissue is feasible under the right circumstances. These cells can be collected from blood, fat, bone marrow, dental pulp, skeletal muscle and other sources. Scientists and clinicians are developing and refining their ability to prepare harvested stem cells and growth factors to be injected into patients for the final repair of diseased or damaged tissue.

Which conditions can be treated in that way?

Osteoarthritis is one of the most common chronic health problems in the world that causes disability and chronic pain with reduced mobility and is a progressive degenerative disease in weight-bearing joints such as the knee.

Osteoarthritis of the knee (KOA) occurs when the cartilage — the joint’s natural cushioning system — breaks down in the knee.

Without this buffer, bones can come into contact with each other, causing pain, stiffness, and a loss of flexibility.

Its incidence and progression are associated with a variety of risk factors. Most of the current treatments focus on symptom management such as physical and occupational therapies, pharmacological intervention for pain management, and surgical intervention with limited success and do not address nor halt the progression of the disease.

Approximately, 9.6% of men and 18% of women who are over 60 years old have symptomatic osteoarthritis worldwide [1, 2].

The major risk factors for OA are older age, obesity, previous injury, sports-related injury, occupational overuse, and genetic background [3, 4]

Stem cells are all over the human body and are classified as self-renewing, postnatal, multipotent cells that can be differentiated into all tissue types of skeletal system and connective tissues such as bone, fat, cartilage, and. These cells produce a vast array of cytokines, growth factors, and anti-inflammatory bioactive molecules

Originally, MSCs were isolated from bone marrow, but more recently they have been successfully isolated from various other tissues such as adipose tissue.

Stem cell for knees treatment

The usual job of joint cartilage is to promote smooth movement of joint surfaces and protect bones from friction. This process allows shock absorption of up to 20 times the weight of the body. It’s essential to physical movement, especially in athletics.

Osteoarthritis is one of the most common chronic degenerative disorders and it very often affects the knee, causing deterioration of its joint cartilage over time.

Osteoarthritis can also begin as a result of a knee injury, such as a ligament tear, tendon damage, or a fracture.

In the face of damage, the joint becomes unstable and this wears down the articular cartilage. From there, the bone can suffer damage as well, in addition to the synovial joint lining, tendons, ligaments, and muscles.

Stem cell therapy for knees is minimally invasive. It’s a procedure that can decrease inflammation, slow down and repair all these forms of damage from arthritis, and delay or prevent knee replacement surgery.

Stem cell knee injections

Adult stem cells can be extracted from bone marrow or fat through simple methods. It’s then concentrated and injected into the knee with image guidance, usually to successful results.

The whole procedure takes one day, it doesn`t require hospitalization.

First period right after the procedure may show a slight increase of pain in the joint due to settlement of the injected cells, however improvement will start soon after and the process of renewal of cartilage will last following months, gradually providing improvement in all ways, pain reduction and mobility increase.

Stem cell therapy for the knee works by:

  • developing into essential cartilage cells
  • putting the inflammation that can worsen arthritis under control
  • releasing proteins called cytokines that slow degeneration of cartilage and reduce pain

Side effects

Stem cell treatment for knees is non-invasive and rarely painful. Side effects are minimal, in form of tenderness and last only for a short period of post-procedural time.

The most frequent experiences after the procedure include mild temporary pain at the injection site, swelling.



The procedure itself lasts only 5-6 hours in our high class Regenerative Rehabilitation Clinic, there is no hospital stay over night, you stay in the full comfort of 5* Hotel while transfer and translator help is also taken care of on your behalf. Contact us, tell us about your problem with knees and we will gladly discuss and organize all related to your treatment as soon as possible.


  1. Chronic rheumatic conditions, “Chronic diseases and health promotion,” 2016, 2016-11-17 16:03:27, Go to WoS://WOS:000333776900001. View at Google Scholar
  2. “Arthritis Information,” 2017,
  3. Silverwood, M. Blagojevic-Bucknall, C. Jinks, J. L. Jordan, J. Protheroe, and K. P. Jordan, “Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis,” Osteoarthritis and Cartilage, vol. 23, no. 4, pp. 507–515, 2015. View at Publisher · View at Google Scholar · View at Scopus
  4. Blagojevic, C. Jinks, A. Jeffery, and K. P. Jordan, “Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis,” Osteoarthritis and Cartilage, vol. 18, no. 1, pp. 24–33, 2010. View at Publisher · View at Google Scholar · View at Scopus